Quantitative subsurface spatial frequency‐domain fluorescence imaging for enhanced glioma resection
نویسندگان
چکیده
منابع مشابه
Wide-field spectrally resolved quantitative fluorescence imaging system: toward neurosurgical guidance in glioma resection.
In high-grade glioma surgery, tumor resection is often guided by intraoperative fluorescence imaging. 5-aminolevulinic acid-induced protoporphyrin IX (PpIX) provides fluorescent contrast between normal brain tissue and glioma tissue, thus achieving improved tumor delineation and prolonged patient survival compared with conventional white-light-guided resection. However, commercially available f...
متن کاملMulti-Scale Spectrally-Resolved Quantitative Fluorescence Imaging System: Towards Neurosurgical Guidance in Glioma Resection
In glioma resection surgery, the detection of tumour is often guided by using intraoperative fluorescence imaging notably with 5-ALA-PpIX, providing fluorescent contrast between normal brain tissue and the gliomas tissue to achieve improved tumour delineation and prolonged patient survival compared with the conventional white-light guided resection. However, the commercially available fluoresce...
متن کاملLaser-induced fluorescence imaging of subsurface tissue structures with a volume holographic spatial-spectral imaging system.
A three-dimensional imaging system incorporating multiplexed holographic gratings to visualize fluorescence tissue structures is presented. Holographic gratings formed in volume recording materials such as a phenanthrenquinone poly(methyl methacrylate) photopolymer have narrowband angular and spectral transmittance filtering properties that enable obtaining spatial-spectral information within a...
متن کاملQuantitative analysis of permeability for glioma grading using dynamic contrast-enhanced magnetic resonance imaging
The objective of the present study was to quantitatively analyze the permeability of tumor entity and peritumor edema in glioma grading, using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). In the present retrospective study, 80 patients underwent T1-weighted DCE-MRI examination at 3.0 T and the pathological results (including astrocytoma and oligodendroglioma) were obtained be...
متن کاملFluorescence-Guided Resection of Malignant Glioma with 5-ALA
Malignant gliomas are extremely difficult to treat with no specific curative treatment. On the other hand, photodynamic medicine represents a promising technique for neurosurgeons in the treatment of malignant glioma. The resection rate of malignant glioma has increased from 40% to 80% owing to 5-aminolevulinic acid-photodynamic diagnosis (ALA-PDD). Furthermore, ALA is very useful because it ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biophotonics
سال: 2019
ISSN: 1864-063X,1864-0648
DOI: 10.1002/jbio.201800271